Twelve-year-old Remember Patience Whipple ("Mem" for short) has just arrived in the New World with her parents after a grueling 65-day journey on the MAYFLOWER. Mem has an irrepressible spirit, and leaps headfirst into life in her new home. Despite harsh conditions, Mem is fearless. She helps to care for the sick and wants more than anything to meet and befriend a Native American.