Meet the Littles, a family like any other but with a few tiny differences! They live in the walls of the Bigg family house where they get everything they need. In return they make sure the Bigg house is always in good repair. When the Biggs go away for the summer the Newcombs come to stay in their house. And the Newcombs are slobs! The mess the Newcombs make attracts one of the Littles biggest enemies: mice! Just when it seems like things can't get any worse, they bring a cat to live with them. How will this little family get out of such big trouble?